The Berndsen Lab focuses on utilizing and developing state-of-the-art cryo-electron microscopy (cryo-EM) techniques in combination with other biochemical, molecular, and computational tools to interrogate the structure and function of important biomolecular systems within the context of human disease. Our aim is to create bridges between basic and translational science with the goal of making discoveries that will both strengthen our fundamental understanding of these systems and accelerate the development of potentially life-saving therapies. To do so, we will not only rely on internal expertise but engage in extensive collaboration with other research laboratories both on the Mizzou campus and around the world.